美国标准菌种收藏所
ATCC
美国模式培养物集存库(American type culture collection)即ATCC www.atcc.org
ATCC成立于1925年,是世界上最大的生物资源中心,由美国14家生化、医学类行业协会组成的理事会负责管理,是一家全球性、非盈利生物标准品资源中心。ATCC向全球发布其获取、鉴定、保存及开发的生物标准品,推动科学研究的验证、应用及进步。
目前,ATCC可以提供以下类别生物标准品:细胞株(3000多种);菌株(15000多种);动植物病毒株(2500多种)以及重组物质等。
美国模式培养物集存库(American type culture collection)即ATCC,于1925年组建,现已成为可信赖的活体微生物、细胞系等获得、保存和发放的国家资源中心。目前,ATCC有29,000多种不同品系可靠的动物细胞和微生物培养体,它能满足各科学团体对可信赖品系的需要。仅1981年就有39,000多培养物发放给全世界的科学工作者,并成功地用冷冻和冷冻干燥的方法保存各种细胞品系。 ATCC是一个非官方(学会单位)无利润的公司,由各科学组织推选成员组成理事会进行管理。现有工作人员125人。参加的科学团体有:美国免疫协会、美国生物化学会、美国细胞生物学会、美国微生物学会、美国动物学会、美国遗传学会、原生动物学会和组织培养协会等16个学术组织。在ATCC可利用各种材料以及工具和设备进行广泛的研究。主要研究项目有:酶联免疫吸附分析技术(ELISA),真核细胞转录的调控,杂交瘤、淋巴类和髓类以及其他细胞系的建立,人突变细胞系的基因蛋白质,借助计算机进行鉴别分析,培养物的特征鉴别和保存技术的改进,关于化学致癌、致畸和致突变的
ATCC is a private, nonprofit biological resource center (BRC) and research organization whose mission focuses on the acquisition, authentication, production, preservation, development and distribution of standard reference microorganisms, cell lines and other materials for research in the life sciences.
History
ATCC was established in 1925 when a committee of scientists recognized a need for a central collection of microorganisms that would serve scientists all over the world. The early years were spent at the McCormick Institute in Chicago until the organization moved to Georgetown University in Washington, DC in 1937. As research in the biosciences expanded, ATCC began to diversify its holdings, and as the collections grew ATCC occupied a series of sites, each providing more storage space. ATCC moved to its current state-of-the-art building in 1998.
Facilities
ATCC activities are housed in a Manassas, Virginia facility. The 126,000 sq. ft. building is monitored constantly by on-site security staff, and electric power is backed up by on-site generators. The repository portion of the facility occupies 18,000 sq. ft. and contains 200 freezers to store biomaterials, including vapor-phase liquid nitrogen freezers, mechanical freezers and cold rooms. The repository space is complemented by 35,000 sq. ft. of laboratory space.
User Communities
The community of users of ATCC products and services is international, and includes researchers in academia and government, as well as private industry. Over 80% of ATCC’s customer base represents academia and industry – about 40% each from universities and private industry. Government customers comprise 6% of the organization’s total. Three-quarters of ATCC customers hail from the U.S., while the remaining 25% are international customers. ATCC maintains a network of authorized distributors around the world. Among the industries represented in ATCC’s customer base are the pharmaceutical, biotechnology, agricultural and diagnostics industries, as well as food, beverage and cosmetics makers and reference and testing laboratories, among others.
Collection Holdings
ATCC’s collections include a wide range of biological materials for research, including cell lines, molecular genomics tools, microorganisms and bioproducts. The organization holds a collection of more than 3,400 human, animal and plant cell lines. The molecular genomics collection at ATCC contains 8 million cloned genes from a host of species, including human, mouse, soybean, rat, monkey, zebrafish and several disease vectors. ATCC’s microorganism collection includes more than 18,000 strains of bacteria, 2,000 different types of animal viruses and 1,000 plant viruses. In addition, ATCC maintains collections of protozoans, yeasts and fungi with over 49,000 yeast and fungi strains and 2,000 strains of protists.
Trademarks
ATCC retains all right, title and interest in the ATCC trademark and trade-name, ATCC®, PRECEPTROL®, UNIPLUS®, Authenticult™, YOUR DISCOVERIES BEGIN WITH US®, EXPRESS-CHECK™, YOUR GLOBAL BIORESOURCE CENTER™, ATCC CULTURES™, ATCC BIOPRODUCTS™, ATCC SPECIAL COLLECTIONS™, ATCC SERVICES™, ATCC Genuine Cultures®, ATCC Licensed Derivative®, BioEscrow™, ATCC Reference Material™, ATCC Fungal Allergen Standard™, ATCC Proficiency Standard™, ATCC Standard Reference Material™ and any and all ATCC Catalog Marks (example ATCC® CRL-1740™) or ATCC specific designations of ATCC Materials sold by ATCC, or other trademarks registered or owned by the ATCC. The ATCC trademark, the ATCC trade-name, or the ATCC Catalog numbers can not be used in any way in connection with any offering, marketing, promotion or sale without ATCC's prior written agreement.